Islet β-cell mass and clinical progression of diabetes mellitus
- VernacularTitle:胰岛?细胞量与糖尿病临床进程
- Author:
Fei GAO
;
Weiping JIA
- Publication Type:Journal Article
- Keywords:
β-cell mass;
Replication;
Neogenesis;
Apoptosis;
Diabetes mellitus
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Normally, pancreatic islet?-cell mass is regulated by?-cell replication, neogenesis, apoptosis and cell size.?-cell mass in diabetic patients is conspicuously less than that in normal persons. Decline of?-cell mass is mainly caused by increased?-cell apoptosis. The change of?-cell mass is clinically becoming more and more important in regard to the progression of diabetes mellitus.
