Sluggish Clearance of Red Blood Cells From Microcirculation in Spleen, Cardiac and Skeletal Muscles.

Author: Seh Hoon SONG ¹
Author Information

1. Department of Biophysics, Health Sciences Centre, The University of Western Ontario, London, Ontario, Canada.
Publication Type:Original Article
MeSH: Animal; Cats; Coronary Vessels*; Erythrocytes/physiology*; Microcirculation; Muscles/blood supply*; Spleen/blood supply*
From:Yonsei Medical Journal 1974;15(1):43-49
CountryRepublic of Korea
Language:English
Abstract: In three isolated organs, spleen, cardiac and skeletal muscles, kinetic studies of red cell washout were carried out by using perfusion of the cell-free, oxygenated Ringer's solution. It is found that in each organ there are slow components for red cells to be emptied out from the vascular lumens ranging 30 to 50 minutes as the desaturation half-time. The slowest decay constants (K) are -1.48 X 10(-3) for spleen, -2.33 X 10(-3) for gastrocnemius muscle, and -4.0 X 10(-3) for cardiac muscle.