THE EXPRESSION OF LECTIN RECEPTORS IN ADENOCARCIN-OMAS OF THE GASTROINTESTINAL TRACT
- VernacularTitle:胃肠道腺癌组织中凝集素受体表达的初步研究
- Author:
Shimin ZHANG
- Publication Type:Journal Article
- Keywords:
expression of lectin receptors;
histochemistry;
glycoconjugates;
gastrointestine;
adenocarcinoma
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Ten cases of gastrointestinal adenocarcinomas were histochemically investigated for their lectin receptors by avidin-biotin-peroxidase complex (ABC) method. Results showed that gastric adenocarcinomas expressed more types of lectin receptors than large bowel adenocarcinomas. Positive rates of G1c/Man-and GlcNAc-specific lectin receptors in those tumors were higher than those of Gal/GalNAc- and Fuc-specific lectin receptoes. From the stomach to rectum, the spectrum of the lectin receptors in pericarcinomatous tissues gradually changed from the gastric type to rectal type. The expression of lectin receptors in gastrointestinal adenocarcinomas was obviously different from that in their corresponding pericarcinomatous tissues. The increase and decrease of lectin receptor expression, the appearance and disappearance of some types of lectin receptors as well as the change of the receptor distribution are indirectly regulated by cellular genome.
