Advances in research of MAGE-A3
- VernacularTitle:肿瘤相关抗原MAGE-A3的研究进展
- Author:
Hao LI
;
Bingya LIU
- Publication Type:Journal Article
- Keywords:
MAGE-A3;
tumor associated antigen;
neoplasm;
diagnosis;
immunotherapy
- From:
China Oncology
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Melanoma-associated antigen MAGE-A3 is expressed in various types of tumors,but not in normal cells except testis and placenta.MAGE-A3 can be presented by both HLA class I and HLA class II molecules after being processed into antigen peptide.MAGE-A3 has recently been widely used in the diagnosis and immunotherapy of tumors.This article reviews the applications of MAGE-A3 in the diagnosis and immunotherapy of tumors.