Caveolae and multidrug resistance of tumor cells
- VernacularTitle:caveolae与肿瘤细胞的多药耐药性
- Author:
Ruihua WANG
;
Yongquan SHI
- Publication Type:Journal Article
- Keywords:
Caveolae;
Multidrug resistance;
Tumor cells
- From:
Cancer Research and Clinic
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Caveolae is a specified micro-domain of plasma membrane, which consists of caveolin and many lipid molecules and membrane proteins. Caveolae plays important roles in internalization of extra-membrane molecules, transmembrane signal transdution and transport of cholesterin. Recent studies indicated that caveolae and its components were up-regulated in multidrug resistant tumor cells and might participate the development of multidrug resistance of tumor cells. This paper concentrated on the role of caveolae in tumor multidrug resistance.
