Relationship of Magnetic Resonance Diffusion-Weighted Imaging to Histology in Chronic Viral Hepatitis
- VernacularTitle:慢性病毒性肝炎组织病理学分级和磁共振弥散成像的对照研究
- Author:
Yang YANG
;
Bin SONG
;
Bi WU
- Publication Type:Journal Article
- Keywords:
Chronic viral hepatitis Magnetic resonance imaging Diffusion-weighted imaging
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of magnetic resonance diffusion-weighted imaging (DWI) to histology in the patients of chronic viral hepatitis. Methods Thirty-five patients of chronic viral hepatitis who received liver biopsy and 10 healthy volunteers were included in this study. All of them underwent DWI on a 3.0T MRI device. Apparent diffusion coefficient (ADC) of the liver were measured respectively when b value were set as 100, 400, 600 and 800 s/mm~2. Biopsy specimens were scored for fibrosis and necroinflammation according to the Knodell histology activity index (HAI). Results When b value was set as 800 s/mm~2, statistical difference was showed between the fibrosis group and the non-fibrosis group, statistical difference was also shown among the different degrees of necroinflammation and fibrosis. Conclusion DWI is a valuable method for grading and staging of chronic viral hepatitis.
