Determination of 10 Kinds of Phthalates in Cosmetics by High Performance Liquid Chromatography
- VernacularTitle:化妆品中10种邻苯二甲酸酯类化合物的高效液相色谱测定法
- Author:
Yanwei YANG
;
Ying ZHU
- Publication Type:Journal Article
- Keywords:
Chromatography, liquid;
Cosmetics;
Phthalates
- From:
Journal of Environment and Health
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a high performance liquid chromatography method for simultaneous determination of 10 kinds of phthalates in cosmetics. Methods 10 kinds of phthalates were separated on a C18 column using methanol-water as mobile phase at a flow rate of 1.0 ml/min, 25℃ column temperature and 280 nm detection wave. Results The detection limit of 10 kinds of phthalates were 0.1-7 mg/L. The precision was less than 3.95% and recovery rates varied from 98.59% to 108.07%. Conclusion The experimental results show that the method is simple, precise and accurate and suitable to simultaneous determination of 10 kinds of phthalates in cosmetics.
