Progress in the treatment of loco-regionally advanced nasopharyngeal carcinoma
- VernacularTitle:局部晚期鼻咽癌治疗新进展
- Author:
Chunyan CHEN
;
Taixiang LU
- Publication Type:Journal Article
- Keywords:
nasopharyngeal carcinoma;
radiotherapy;
chemotherapy;
concurrent chemoradiotherapy
- From:
China Oncology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
90% with better sparing of the surrounded normal tissue.However,the metastasis rate is still 20%-25%,which limits the improvement of overall survival(OS).To consolidate the local control rate and reduce the metastasis rate,it is necessary to combine chemotherapy with radiotherapy.According to clinical randomized studies and meta-analysis,chemotherapy can improve the OS of loco-regionally advanced nasopharyngeal carcinoma by more than 6% with radiotherapy alone as baseline.Concurrent chemo-radiotherapy is the most promising strategy to cope with the disease.This review has summarized the progress in the area of combination of chemotherapy and radiotherapy for the treatment of loco-regionally advanced nasopharyngeal carcinoma.
