Effect of immuno-intervention with PGE_2 on TNF-?,IL-10,SOD and NO in rats attacked by vibrio vulnificus
- VernacularTitle:PGE_2免疫干预对大鼠Vv攻击后TNF-?、IL-10以及SOD和NO的影响
- Author:
Qiaomin ZHENG
;
Tao ZHU
;
Liping ZHOU
;
Pingan YU
- Publication Type:Journal Article
- Keywords:
PGE_2;
Vibrio vulnificus;
TNF-?;
IL-10;
SOD;
NO
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study of immuno-intervention with prostaglandin E2(PGE_2) on tumor necrsis factor(TNF-?),interleukin 10(IL-10),SOD and NO in rats attacked by vibrio vulnificus.Methods:27 normal rats and 27 hepatopathy rats,they were divided into Vv attacked group,ofloxacin treatment group and combined PGE_2 with ofloxacin protect group(n=9).Results:The result of cytokines detection showed that serum IL-10 and SOD level of combined PGE_2 with ofloxacin protect group was significantly higher than that of ofloxacin treatment group,however,TNF-? and NO level of PGE_2 immuno-protect group were significantly lower than those of ofloxacin treatment group(P
