New pathological ultrastructure observation of compressive spinal cord injury in rats
- VernacularTitle:大鼠压迫性脊髓损伤的特征性超微病理表现
- Author:
Hengsheng SHU
;
Jianhua YU
;
Zhiming SUN
- Publication Type:Journal Article
- Keywords:
Spinal cord injury;
Ultrastructure;
Traumatic cell
- From:
Orthopedic Journal of China
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To observe the characteristic ultrastructure changes of compressive spinal cord injury.[Method]Animal model of compressive spinal cord injury was made by modified Allen's method.Pathological changes of spinal cord tissues were observed with transmission electronic microscopy after 4 weeks.[Result]The characteristic ultrastructure changes of compressive spinal cord injury were observed obviously.It was necrosis without inflammatory cell reaction.The single-direction break of myelin sheath and the traumatic cell could be observed.They were all formed by the reason of biomechanics.These two characters were the characteristic ultrastructure changes of compressive spinal cord injury.[Conclusion]These new ultrastructure observations can provide certain materials for the basal explore of compressive spinal cord injury.