Preparation and biocompatibility of acellular trachea matrix
- VernacularTitle:脱细胞气管基质制备及其生物相容性研究
- Author:
Guilin HUANG
;
Longjiang LI
;
Xueying LI
- Publication Type:Journal Article
- Keywords:
Acellular trachea matrix;
Biocompatibility;
Artificial salivary gland
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To prepare an acellular matrix from trachea of rabbits and SD rats, and to investigate its biocompatibility.Methods: A modified detergent and enzyme link extraction procedure was performed to remove cells from the trachea of SD rats and rabbits. The histology, topography of inner-surface and biocompatibility were studied by morphological observation,cell culture and in vivo transplantation respectively.Results:The acellular trachea matrix did not inhibit the growth and amylase secretion of allogenic salivary gland cells cultured on it.The allogenically transplanted acellular trachea matrix did not result in inflammation reaction of the host tissue,could integrate with surrounding tisses.Conclusion:The acellular trachea matix is biocompatible.