The influence of hydroxyapatite coating on sandblasted and acid-etched surface of titanium dental implants on the biologic characteristics of marrow-origin osteoblasts
- VernacularTitle:钛种植体SLA表面HA涂层对骨髓源成骨细胞生物学特性的影响
- Author:
Chengyue WANG
;
Baohong ZHAO
;
Hongjun AI
- Publication Type:Journal Article
- Keywords:
Ion beam assisted deposition;
Shot blasted;
Acid-etching;
Hydroxyapatite;
Osteoblasts
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of hydroxyapatite(HA) coating on sandblasted and acid-etched(SLA) surface of titanium dental implants(HA-SLA-Ti) on the biologic characteristics of marrow-origin osteoblasts(MOOBs).Methods:Coating of HA on the SLA surface of titanium dental implants were formed by ion beam assisted deposition (IBAD) method. MOOBs,cultured in vitro,were seeded onto the surface of HA-SLA-Ti and SLA-Ti respectively, the growth of MOOBs on the two kinds of samples were observed by scaning electron microscope.The proliferation index, alkaline phosphatase(AKP) activity, osteocalcin(BGP) content of MOOBs and mRNA relative expression level of osteopontin(opn) were examined and compared between two groups.Results: MOOBs grew well on the surface of HA-SLA-Ti; the proliferation index, AKP activity and BGP content of MOOBs were higher in HA-SLA-Ti group than those in SLA-Ti group(P
