Clinical study of chemoradiation therapy in rectal cancer
- VernacularTitle:直肠癌的辅助放化疗的临床研究
- Author:
Gang CAI
;
Zhen ZHANG
- Publication Type:Journal Article
- Keywords:
rectal cancer;
surgery;
postoperative radiation;
preoperative radiation;
chemoradiation
- From:
China Oncology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Rectal cancer is a common malignant tumor in the gastrointestinal system.For the patients with resectable but high-risk rectal cancer,neoadjuvant and adjuvant chemoradiation plus surgery may improve local control.Compared to adjuvant chemoradiation,neoadjuvant chemoradiation showed the advantage of sphincter preservation.When the goal of preoperative chemoradiation was sphincter preservation,conventional radiotherapy was recommended.Through the analysis of the patients with 5-year survivals,the radiation had a similar impact on the survival as the chemotherapy alone for the patients with the intermediate risk factors.The impact on local control need to be further investigated before recommending chemotherapy alone for those subset patients.Advances in preoperative irradiation,postoperative irradiation and the comparison of preoperative irradiation with postoperative irradiation are also reviewed in this article.
