Clinical characteristics of nineteen vasculitis patients associated with propylthiouracil-induced antineutrophil cytoplasmic antibody
- VernacularTitle:19例丙基硫氧嘧啶引起抗中性粒细胞胞浆抗体相关小血管炎的临床分析
- Author:
Ying GAO
;
Minghui ZHAO
;
Hua YE
;
Xiaohui GUO
- Publication Type:Journal Article
- Keywords:
Propylthiouracil;
Antibody, antineutrophil cytoplasmic;
Vasculitis;
Hyperthyrodism
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Clinical data were analysed in 19 patients with propylthiouracil (PTU)-induced antineutrophil cytoplasmic antibody associated vasculitis. Among them, 17 patients (89.5%) were diagnosed as Graves′ disease originally. The duration of PTU therapy in 18 patients was more than two years. Multi-organ involvement was common, with 15 patients (78.9%) involved in kidneys and 8 patients (42.1%) involved in lungs. The prevalences of arthralgia, skin rash and fever were also high. All patients withdrew PTU, and some with severe organ involvements received prednisone and immunosuppressant.
