Infusion of No.2 Fluorocarbon Blood Substitute in Normal Volunteers
- VernacularTitle:Ⅱ号氟碳代血液正常人体试验
- Author:
Zhihuan YANG
- Publication Type:Journal Article
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Fifty to 145 ml of No. 2 fluorocarbon blood substitute was intravenously given to 10 normal adult volunteers ( 7 male and 3 female) . Their vital signs were stable during and after the infusion. The ECG, the cardiac, hepatic and renal functions, the mutagenicity test and the routine urine test were maintained in the normal range. NO overt changes in the blood picture except a slight elevation of white count were found at the beginning of the infusion. Transient changes were observed in the function of platelets and the coagulofibrinolytic and immune systems.These results suggest that the infusion of No. 2 fluorocarbon blood substitute is rather safe and the possibility qf its clinical application is great bat further investigation is essential to find out measures to prevent and treat the ana-phylactoid reactions of this fluorocarbon emulsion observed in our study.
