Preparation of monoclonal antibody against human colorectal cancer and its application in tumor research
- VernacularTitle:抗人结肠癌相关抗原单克隆抗体的制备及初步研究
- Author:
Yu SONG
;
Xiaoyan LIU
;
Ping ZHANG
;
Qiang WU
;
Zhenshan XU
;
Lihua SONG
- Publication Type:Journal Article
- Keywords:
Monoclonal antibody;
Colorectal cancer;
Tissue microarray
- From:
Chinese Journal of Immunology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To produce the mAb which specifically reacting with colorectal cancer confirmed by the tissue microarray technology.Methods:The mice were immunize with LOVO, and the mAb were screened by indirect cell ELISA and immunohistochemistry.Results:A McAb was obtained which can react to the colon cancer, but very little or not to normal tissue and other caner tissues.Conclusion:A McAb which can react to the colon cancer have been obtained,and the McAb can be useful on clinic for diagnosis and prognosis of colorectal cancer.
