Clinical efficacy of bleomycinum A5 in treatment of infant hemangioma in eye
- VernacularTitle:平阳霉素注射治疗婴幼儿眼部血管瘤的临床效果
- Author:
Daoman XIANG
;
Hongmei ZHOU
;
Guangqiang FENG
;
Xinyun XIONG
- Publication Type:Journal Article
- Keywords:
Children;
Eye;
Hemangioma;
Bleomycinum
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2002;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of bleomycinum A5 on different type and site of eye hemangioma in infant. Methods 45 infant cases (23 females and 22 males) of hemangioma of eye were studied from the outpatient deparment of our hospital between 1996 and 2001. The powder of bleomycinum A5 was dissolved in 2 % procaine solution. The mixed liquid was injected uniformly into the mass of hemangioma of eye until it appeared offwhite.Results After the injection, the masses of hemangioma of eye swelled and atrophied subsequently, and the reaction disappeared within 7 days. The appearance of the local tissue turned from red to white. The hardness of it became soft several months after injection. 43 of 45 (95.5 %) patients healed after 2~5 times injection. Conclusions This method is proved effective to different type of hemangioma in infant eye, with minor damage, mild scar formation and good appearance. The side effect includes delay of development in the socket of orbit bone, local tissue necrosis and pigmentation of the skin.
