Postoperative radiotherapy for stage Ⅱ/Ⅲ rectal cancer
- VernacularTitle:Ⅱ/Ⅲ期直肠癌术后辅助放疗
- Author:
Xuejun MA
;
Xiaomao GUO
;
Zhen ZHANG
;
Ji ZHU
;
Yan FENG
- Publication Type:Journal Article
- Keywords:
rectal cancer;
radiotherapy;
radiation dose;
prognosis
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
60 Gy.The 5-year local control rates are 92%,71% and 87% respectively(P=0.9194),and 5-year overall survival rate are 68%,62% and 53% respectively(P=0.4194).There is no significant difference of overall survival and local control rate between these three dose groups.Five patients with dose of more than 50Gy died of late toxicities.Conclusions:Adjuvant radiotherapy for Stage Ⅱ and Ⅲ patients with rectal cancer dose not show dose response.There is no improvement of local control and survival due to the escalation of dose.The dose of conventional radiotherapy is better at less than 50Gy.Overdosage may lead to severe toxicities.
