The preliminary study on the expression of estrogen receptor ? and ? in temporomandibular joints of Sprague-Dawley rats
- VernacularTitle:雌激素受体?、?在大鼠颞下颌关节中表达的初步研究
- Author:
Shibin YU
;
Meiqing WANG
;
Wei ZHAO
- Publication Type:Journal Article
- Keywords:
Temporomandibular joint;
Cartilage;
Estrogen receptor;
Condyle
- From:
Journal of Practical Stomatology
1996;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of estrogen receptor ? and ?(ER? and ER?) in temporomandibular joints(TMJs) of Sprague-Dawley rats.Methods:The expression of ER? and ER? in TMJs was examined by SABC technique of immunocytochemistry, meanwhile the co-expression of them was detected by double-staining technique of immunocytochemistry.Results:①Intense ER? and ER? immunoreactivity was localized in the hypertrophic layer of condyle cartilage,and some immunoreactivity was found in osteocytes of mandible and temporal bone. ②The immunoreactivity of ER? and ER? was found in both nuclei and cytoplasms. Most of immunoreactivity of ER? was localized in nuclei, while ER? was distrubuted more evenly. ③The expression of ER? was wider than that of ER?.Conclusions:TMJ is one of target organs of estrogen.The expression of ER? is different from that of ER?,which suggests there may be different mechanisms directed by ERs.
