Expression of ?-catenin during check pouch carcinogenesis in golden hamster
- VernacularTitle:金黄地鼠颊囊癌变过程中?-连接素表达的实验研究
- Author:
Xiaoli LI
;
Wenxin GAO
;
Yang GAO
- Publication Type:Journal Article
- Keywords:
?-catenin;
Golden hamster check pouch;
Carcinogenesis;
Immunohistochemistry
- From:
Journal of Practical Stomatology
1996;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate ?-catenin expression during check pouch carcinogenesis in golden hamster.Methods:Expression of ?-catenin was examined with immunohistochemical SABC method in 23 cases of check normal buccal epithelium of golden hamster,22 of hyperplasitic epithelium,22 of dysplastic epithelium,29 of squamous cell carcinoma.Results:Normal buccal epithelium showed strong pericellular staining in the basal,suprabasal and prickle cell layers.Positive rates(%) of ?-catenin in normal buccal epithelium,hyperplastic epithelium,dysplastic epithelium and squamous cell carcinoma were 100,100,77.3 and 41.4 respectively.Conclusion: The decreased expression of ?-catenin may be related to the carcinogenesis of golden hamster check pouch.
