A primary study on the antimutagenesis activity of fruit-vegetable beverage(carrot juice)
- VernacularTitle:果蔬饮料胡萝卜汁拮抗致突变物作用的初步研究
- Author:
Feng CHEN
;
Huanzao LUO
- Publication Type:Journal Article
- Keywords:
Fruit-vegetable beverage;
Ames'point-circle test;
Antimutagenesis inhibition rate
- From:
Cancer Research and Clinic
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the antimutagenesis of carrot juice and to provide necessary data for the development of fruit-vegetable beverage. Methods Revised rat salmonella mutagenicity test was used, strains had been cultured for 48 hours at a constant temperature of 37 ℃. We counted the anaphysis strains produced in the paper circle, and judged whether there was a antimutagenesis effect according to the difference of the anaphysis strain number between the samples and the dissolvent controls. We also judged the mutagensis effect of the samples based on the anaphysis strains outside the paper circle. Results TA98-TA100 strains were all inside the normal scope, mutagenesis effect of all samples had not been observed. Conclusion Under our laboratory conditions, the inhibition rate of sample Ⅰ,Ⅳ on the induction of N-methy1-N/-nitroso-N-nitrosoguanidine(MNNG) to TA100-S9 and of sample Ⅱ, Ⅲ on the induction of aflatoxin B1( AFB1) to TA+S9 was high, and dose-response effect was obvious, also the inhibition effect of both sample Ⅰ,Ⅱ on the induction of AFB1 and that of sample Ⅰ on the Benzo(a)pyrene (BAP) to TA100+S9 was relatively high, but there was no dose-response effect exist.
