Evaluation of cardiac systolic function of adriamycin cardiomyopathy by quantitive tissue velocity imaging: an animal study
- VernacularTitle:定量组织速度成像评价阿霉素性心肌病心脏收缩功能的研究
- Author:
Xiaoyi CHEN
;
Ruiqiang GUO
;
Lidan HAO
;
Congxin HUANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Cardiomyopathies;
Doxorubicin;
Ventricular function,left
- From:
Chinese Journal of Ultrasonography
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of quantitive tissue velocity imaging(QTVI) in assessing the systolic myocardial function of adriamycin cardiomyopathy.Methods Conventional echocardiography and QTVI were performed in 7 rabbit models with adriamycin cardiomyopathy and 5 health rabbits as control.The basic segments of interventricular septum of apical 4-chamber view and left ventricular post wall of parastenal left ventricular long axis view were sampled to measure maximal velocity(VIVS,VLVPW),displacement(DIVS,DLVPW),strain rate(SRIVS) and strain(?IVS) in systole.Pre-eject period(PEP) and ratio of pre-eject period and eject time(PEP/ET) were measured with electrocardiography and Doppler spectrums of mitrial and aortic orifices.Results Compared with control,VIVS,DIVS,SRIVS,?IVS and VLVPW,DLVPW decreased(P0.05).Conclusions The indices of QTVI are more sensitive to evaluate systolic function changes than EF,and QTVI may be an optimal method to early diagnose and access of adriamycin cardiomyopathy.
