The expression of p53 and VEGF in bladder transitional cell carcinoma and its clinical significance
- VernacularTitle:膀胱移行细胞癌组织中p53和血管内皮生长因子表达的关系及临床意义
- Author:
Hongtao YAN
;
Baisheng GONG
;
Yong LIAO
;
Hong YANG
;
Zhaoxiang CHEN
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Carcinoma;
p53 gene;
Vascular endothelial growth factor;
Immunohistochemistry
- From:
Chinese Journal of Urology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of p53 and vascular endothelial growth factor(VEGF) in bladder transitional cell carcinoma(BTCC) tissue and its relationship with the clinicopathologic parameters,and to understand the role of p53 and VEGF in the progression of tumors.Methods The expression of p53 and VEGF in 86 cases of BTCC were determined by immunohistochemical LDP methods.Results The positive expression rates of p53 and VEGF in 86 cases of BTCC were 46.51% and 66.28%,respectively.The positive correlation was noted between p53 expression and VEGF expression(P
