Expression of matrix metalloproteinases mRNA in growing rats masticatory muscle after functional mandibular protrusion
- VernacularTitle:功能性矫治器引导大鼠下颌前伸后咀嚼肌基质金属蛋白酶mRNA的表达
- Author:
Huiling SUN
;
Hong ZHOU
;
Min ZOU
- Publication Type:Journal Article
- Keywords:
masticatory muscle;
MMPs;
mRNA;
mandibular protrusion;
RT-PCR
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate molecular changes in growing rats masticatory muscle after functional mandibular protrusion.Methods SD rats were randomly divided into eight groups as control 3d,7d,14d,21d and experimental 3d,7d,14d,21d.The RTPCR and qPCR methods were used to find expression and any differences of mRNA of MMPs in growing rats masticatory muscle after functional mandibular protrusion. (Results)(① Expression) of MMP-2,MMP-9 mRNA expressed in all growing rats masticatory muscle.② Expression differences of MMP-2 and MMP-9 mRNA in 3d,21d were found between control and experimental groups after functional mandibular protrusion.Conclusion ①MMP-2 and MMP-9 mRNA participate in masticatory muscle normal development.(② MMPs) mRNA involve changes in growing rats masticatory muscle after functional mandibular protrusion.
