Study of expression of CD_(105), CD_(31) and relationship with the biological behavior in gastric cancer
- VernacularTitle:胃癌组织中CD_(105)和CD_(31)的表达及其与胃癌生物学行为的关系
- Author:
Qingxing HUANG
;
Minsheng BAO
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
CD105;
CD31
- From:
Cancer Research and Clinic
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of CD105 and CD31 and relationship with the biological behavior in gastric cancer tissue. Methods Immunochemical method was adopted to detect the microvessel density(MVD) of CD105 and CD31 in 63 cases of gastric cancer and 20 cases of chronic gastritis. Results The mean value of CD105-MVD and CD31-MVD were respectively 40.97?15.67 and 25.87?10.54 in gastric cancer, which was higher than those in chronic gastritis, the difference was significant (P 0.05). Conclusion CD105 was better than CD31 in staining gastric cancer tissue. Expression of CD105 was closely related to the biological behavior of gastric cancer; detection of CD105 was recommended to precisely assess tumor stage, direct cancer therapy and predict prognosis.
