A clinicopathologic and immunohistochemical study on 87 cases of gastrointestinal stromal tumors
- VernacularTitle:胃肠道间质瘤87例临床病理分析
- Author:
Lingjing MU
;
Shanxian LOU
;
Shoutian ZHU
;
Qingwei LIU
- Publication Type:Journal Article
- Keywords:
Pathological characteristics;
Gastrointestinal stromal tumors
- From:
Cancer Research and Clinic
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical, pathological and immunohistochemical characteristics of gastrointestinal stromal tumors (GISTs). Methods 87 cases of GISTs were studied with conventional histopathological and immunohistochemical stains. Results All patients were adults, age range 28 to 73 years (mean 53 year), the tumors were situated in stomach (56 cases), in small intestine (29 cases), in colon (2 cases). The tumors had two kinds of cells: spindle cells and epithelioid cells, they were different in proportion. Immunohistochemically, vimentin were all positive, CD117 and CD34 showed diffuse strong expression, SMA and S-100 were positive when the tumors differentiated to smooth muscle and nerve. Conclusion GISTs predominantly occurred in middle aged or old patients, the tumors were composed of spindle cells and epithelioid cells. The immunohistochemical characters were positive for CD117 and CD34.
