Structure and function of cell toxin gelonin and its application prospect in anti-cancer treatment
- VernacularTitle:细胞毒素Gelonin的结构功能及其在抗癌治疗中的应用前景
- Author:
Yanfeng QU
;
Sutang GUO
;
Jingming YUAN
- Publication Type:Journal Article
- Keywords:
Cell toxin gelonin;
Anti-cancer treatment
- From:
Cancer Research and Clinic
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Ribosome-inactivating proteins(RIPs), a natural anti-caner protein from some advanced plants, includes single-chain robosome-inactivating proteins (type Ⅰ) and double-chain ribosome-inactivating proteins (type Ⅱ). Gelonin, relative molecular weight around 30?103, belongs to single-chain ribosome-inactivating proteins. This review is about the structure and biological activity of cell toxin Gelonin and application prospect in anti-cancer treatment.