EFFECTS OF ANTI-DENDRITIC CELL MONOCLONAL ANTIBODY ON EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS
- VernacularTitle:抗树突状细胞单克隆抗体对小鼠实验性自身免疫重症肌无力的作用
- Author:
Shisong JIANG
- Publication Type:Journal Article
- Keywords:
dendritic cell;
monoclonal antibody;
myasthenia gravis
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
The experimental autoimmune myasthenia gravis (EAMG) was induced by-inoculating C57BL/6 mice with partially purified acetylcholine receptor (AchR) plus complete Freund's adjuvent. The clinical signs of mice included decrement of striated muscle contraction, proliferative response of splenic lymphocytes to AchR and production of sera anti-AchR antibody. Pretreatment of the mice with anti-dendritic cell monoclonal antibody 33D1 prevented the occurrence of EAMG
