Suppressor of cytokine signaling-3, interleukin-6 and insulin resistance
- VernacularTitle:细胞因子信号转导抑制因子3与白细胞介素6、胰岛素抵抗的关系
- Author:
Chunmei YANG
;
Yancheng XU
- Publication Type:Journal Article
- Keywords:
Suppressor of cytokine signaling-3;
Interleukin-6;
Insulin resistance
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Suppressor of cytokine signaling (SOCS)-3 is a negative regulator of interleukin (IL)-6 signal transduction. The results showed that IL-6 was not only correlated with insulin resistance but also capable to induce the expression of SOCS-3.Thus the high expression of SOCS-3 mRNA may contribute to one of the mechanisms of IL-6 dependent insulin resistance.
