Effects of anisodamine on level of neurotensin in the plasma and lung homogenate of rat with brain trauma
- VernacularTitle:山莨菪碱对脑外伤后急性肺损害大鼠神经降压素含量的影响
- Author:
Xuehua CHEN
;
Xiaoyang LUO
;
Zhenhua HU
;
Runhua WU
;
Sufen ZHANG
;
Yanling CHEN
- Publication Type:Journal Article
- Keywords:
Brain injuries;
Neurotensin;
Anisodamine;
Plasma;
Lung homogenate
- From:
Chinese Journal of Trauma
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of anisodamine on levels of neurotensin in the plasma and lung homogenate during acute lung injury in rats after brain trauma.Methods The level of neurotensin in the plasma and lung organizes after brain trauma and that after administration with anisodamine were determined by radioimmunoassay(RIA).Results Level of neurotensin in the plasma and lung homogenate of rat with brain trauma was obviously higher than that in normal control group but significantly lower than that in anisodamine group.Conclusion Increase of neurotensin in the plasma and lung homogenate may be due to causing lung injury after brain trauma.Anisodamine can exert protective effect on acute brain injury by reducing level of neurotensin in in the plasma and lung homogenate.
