Application of proteomic techniques in searching lung cancer biomarkers
- VernacularTitle:蛋白质组学及其研究技术在肺癌分子生物标志物研究中的应用
- Author:
Bin QIAO
;
Wenjing WANG
- Publication Type:Journal Article
- Keywords:
proteome;
lung cancer;
tumor biomarker
- From:
China Oncology
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer is one of the malignant tumors with a high morbitity and mortality in the world.During its neoplastic development, a set of changes in protein expression occurs.The changed proteomic profile of cancers—tumor biomarkers could guide clinical decision-making.Proteomic methods are widely used in identification of tumor biomarkers.To reduce the mortality of lung cancer and improve its therapy,many studies on the identification of this tumor biomarker are being carried out.This review summarizes the main strategies and technology in proteomics and its application in identification of lung cancer biomarkers.