Interaction of GSTM1, GSTT1 Polymorphism and Air Pollution in Asthma
- VernacularTitle:GSTM1和GSTT1基因多态性与大气污染的交互作用对哮喘的影响
- Author:
Shuhua XI
;
Li GUO
;
Rong QI
- Publication Type:Journal Article
- Keywords:
Air pollution;
Gene polymorphism;
Asthma;
Interaction
- From:
Journal of Environment and Health
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). In stratified studies, risk of asthma in individuals with null genotype of GSTM1 is 2.667 times of that with wild genotype after exposure to light air pollution. Risk of asthma in individuals living in heavy air pollution area is 2.125 time of that in light pollution area for all wild genotype of GSTM1 individuals, but without statistical significance. Conclusion It was not found that the relationship between GSTM1, GSTT1 polymorphism and asthma. Synergism of genotype of GSTM1, GSTT1 and air pollution was not also seen in this study.
