The role of CD2 in acute rejection after small bowel transplantation in rats
- VernacularTitle:大鼠小肠移植排斥反应时外周血T淋巴细胞上CD2分子的表达
- Author:
Gang JI
;
Yan LIN
;
Weizhong WANG
- Publication Type:Journal Article
- Keywords:
Intestine,small;
Transplantation;
Antigens,CD2;
Rats
- From:
Chinese Journal of Organ Transplantation
2003;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of CD2 in peripheral blood T lymphocytes in acute rejection after small bowel transplantation (SBT) in rats.Methods Three groups were set up: Group A (n=18), receiving sham operation and feeding of common feedstuff; Group B (n=18) receiving SD rat to SD rat iso-series SBT and the treatment of routine liquid infusion and antibiotics after operation; Group C (n=18) receiving SD rat to Wistar rat taniso-series SBT and the same post- operation treatments as in group B. Samples of grafts and peripheral blood in the three groups were collected on the day 3, 5 and 7 respectively after SBT for detection of flow cytometry. The intestinal grafts were obtained for pathological examination.Results The survival time of rats in group C, group B and group A was 7.0? 2.1, 33.3? 2.3 and more than 90 days, respectively. There was significant difference between group C and groups A, B (P
