The design and animal study of a new posterior lumbar interbody fusion cage
- VernacularTitle:新型后路腰椎椎间融合器的研制和动物实验研究
- Author:
Xin HONG
;
Xiaotao WU
;
Zubin MAO
- Publication Type:Journal Article
- Keywords:
Lumbar vertebrae;
Spinal fusion;
Prosthesis design;
Biomechanics
- From:
Chinese Journal of Orthopaedics
1998;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To design a new type of posterior lumbar interbody fusion cage made of NiTi shape-memory alloy and to evaluate its histological and biomechanical behavior through animal study. Methods This study contained three steps of experiments which was posterior lumbar interbody fusion using different fusion materials and devices. At the first step, 12 sheep lumbar functional spinal units were randomly divided into 4 groups with 3 specimens in each group. There was one group with autogenous iliac crest bone dowel(IG), one group with interfix lumbar cage(cage), one group with NiTi-TFC(NT) and one group served as control group. Nondestructive biomechanical tests were carried out for each group. At the second step, 15 sheep were randomly divided into three groups with 5 specimens in each group. There was one group with cage and autogenous iliac crest graft, one group with NT and iliac crest and one group served as control group. All the animals were undergone imaging study regularly to evaluate the change of the intervertebral space heights and the process of fusion. At the third step, all animal from the second step were sacrificed 6 months later for histological analysis of the operated segments. All the data were statistically analyzed using SPSS 7.0. Results The strength and axial stiffness of the autogenous iliac crest bone dowel graft group and the control group were significantly different from the NT and cage group(P
