Expression and significance of p27 and Ki-67 in breast invasive ductal carcinoma
- VernacularTitle:p27和Ki-67在乳腺浸润性导管癌中的表达及意义
- Author:
Qilin SHI
- Publication Type:Journal Article
- Keywords:
Breast invasive ductal carcinoma;
p27;
Ki- 67;
Pathology;
Immunohistochemistry
- From:
Cancer Research and Clinic
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of the expression of p27 and Ki-67 with the clinicopathologic features in breast invasive ductal carcinoma. Methods S-P immunohistochemical staining was performed to examine the expression of p27 and Ki-67 in 60 specimens of breast invasive ductal carcinoma. Results The low p27 expression rate was 45.0 %(27/60), low expression in breast cancer was associated with larger tumor, nerve/vessel invasion, lymph node metastasis and histological grade(P
