Radiographic imaging study of the correlation between subchondral bone marrow edema and pain in knee osteoarthritis
- VernacularTitle:软骨下骨髓水肿与膝骨关节炎疼痛相关性的影像学研究
- Author:
Xiaopeng GENG
;
Baicheng CHEN
;
Xia WANG
- Publication Type:Journal Article
- Keywords:
Osteoarthritis, knee;
Pain;
Magnetic resonance imaging
- From:
Chinese Journal of Orthopaedics
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate whether the presence of subchondral bone marrow edema (BME)in magnetic resonance imaging(MRI) are associated with the different levels of knee pain among the patients suffering osteoarthritis(OA). Methods Based on rating scale of pain, 264 patients with knee OA were divided into three groups: 47 in the no pain group, 184 in the mild pain group, 33 in the moderate or severe pain group. Contingency table analyses and rank sum tests were used to compare the difference of OA stage and BME score among these groups. OA was classified by the X-ray as the Kellgren-Lawrence(K-L) scoring scale system: 52 mild(K-L Ⅱ degree), 142 middle(K-L Ⅲ degree), 70 severe(K-L Ⅳ degree); while BME was identified from MRI: 69 with grade 0(no BME), 127 with grade 1(small BME), 68 with grade 2(large BME). Results There were no statistical significance of OA stage among three pain groups(?2=5.251, P=0.263), though severe OA were more likely to occur in moderate or severe pain group as compared with the no pain and mild pain groups(42.4% vs 23.4% and 24.5%). Also in the three groups, the prevalence of each score BME was of great significant difference(?2=28.157, P
