Bacterial infections following liver retransplantation
- VernacularTitle:再次肝移植后并发细菌感染的临床分析及治疗
- Author:
Yong JI
;
Xiaoshun HE
;
Xiaofeng ZHU
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Reoperation;
Bacterial infections
- From:
Chinese Journal of Organ Transplantation
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the epidemiology, prophylaxis and treatment of bacterial infections after orthotopic liver retransplantation.Methods A retrospective study on bacterial infections in 22 patients undergoing othotopic liver retransplantation was carried out.Results Bacterial infections were confirmed in 8 of 22 preoperation and in 20 of 22 (90.9 %) postoperation. The median time of bacterial infections was 7 days after liver retransplantation. Fifty-one pathogenic organisms including 25 types were separated. The most commonly seen infected sites were biliary tract (50.0 %, 11/22), abdomen (45.4 %, 10/22), respiratory tract (36.4 %, 8/22), blood (31.7 %, 7/22), incision ((9.1) %, 2/22), bowel (4.5 %, 1/22), veins with venipuncture (4.5 %, 1/22). Seven cases of sepsis died.Conclusion The infectious rate after liver retransplantation is high and the types of bacterial disseminating loosely on organs are varied. The mortality will be increased if the patients develop sepsis. Reasonable use of immunosuppressants, selection of antibiotics and the supporting therapy are the keys to prevent and treat infections following liver retransplantation.
