Correlation of Spiral CT Features and Angiogenesis,Expression of TP,TGF-?_1 in Hepatocellular Carcinoma
- VernacularTitle:肝细胞癌SCT表现特征与血管生成及TP和TGF-?_1表达的相关性研究
- Author:
Xiufeng SONG
;
Bin WANG
;
Huijie QIAO
;
Maoyi ZHOU
;
Lixin LI
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
neovascularization;
thymidine phosphorylase,platelet-derived endothelialcell growth factor;
transforming growth factor-?_1;
tomography,X-ray computed
- From:
Journal of Practical Radiology
1992;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the correlation between the contrast enhanced features on spiral computed tomography(SCT) and microvessel density(MVD),TP,TGF-?_1 expression.Methods Forty seven cases with hepatocellular carcinoma(HCC) proved pathologically were examined with enhanced dual-phase SCT scanning at the arterial phase and the portal vein phase.The SCT features including the size of HCC lesions,enhanced patterns,capsule patterns,the diameter of tumor,intrahepatic daughter foci and tumor-emboli in portal veins were studied.The expression of TP,TGF-?_1 and MVD were detected by immunohistochemical SP method.The enhanced features of SCT were compared with the immunohistochemical results and clinicopathological characteristics of HCC.Results TP and MVD were correlated with metastasis and capsule patterns(P0.05).Conclusion The expression of TP,TGF-?1 and angiogenesis of HCC can be evaluated by some SCT features in a certain degree.
