Breast cancer in older women
- VernacularTitle:老年人乳腺癌
- Author:
Bin ZHANG
- Publication Type:Journal Article
- Keywords:
breast cancer;
biologic behavior;
psychosocial factors;
surgery;
endocrine therapy;
chemotherapy;
radiotherapy;
elderly
- From:
China Oncology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer in the elderly seems to be less aggressive than in the younger patients.Older women tend to have more localized disease or locally advanced breast cancer.Older women more frequently have phgsiological changes as well as concurrent disease that planning may limit the choice of therapy.Patient's performance status and tumor's biologic behavior should be considered when primary treatment of breast cancer other than tumor stage at presentation.Surgical operation is one of the major means for the treatment of operable breast cancer.In early breast cancer women who have ER-positive tumor that can be treated with breast conservation,or with sentinel node biopsy followed by breast irradiation and endocrine therapy,or without breast radiation.The patients with locally advanced breast cancer or who have larger,ER-positive tumor,or clinically-positive axillary nodes can be given preoperative endocrine therapy with 3~(rd) generation of aromatase inhibitors to try to convert to limited surgery.Adjuvant chemotherapy can be considered for older women with ER-negative tumor whose risk of systemic recurrence is high and who are in good health.Strict adherence to indications of adjuvant radiotherapy should be carried out for older women with breast cancer.
