Effects of selenium and iodine deficiency on the contractibility of rat thoracic aorta
- VernacularTitle:低硒、低碘对大鼠离体胸主动脉血管收缩性的影响
- Author:
Yufei BAI
;
Xin MA
;
Hongjuan WANG
;
Xiaojuan ZHANG
;
Xiong GUO
;
Ruijuan ZHANG
- Publication Type:Journal Article
- Keywords:
selenium;
iodine;
thoracic aorta;
endothelium
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of selenium and iodine deficiency on the contractibility of rat thoracic aorta and probe into its mechanisms.Methods Isolated vascular methods were used to study the effects in different groups.Results The contraction of rat thoracic aorta of the groups with selenium and iodine deficiency was less than that of the normals(P(0.05));sodium selenite(0.1mol/L) had no effect on rat aortic contraction,but was significantly synergic with the contraction induced by KCl combined with NE(P