The expression of interleukin-1? and matrix metalloproteinase-9 in middle ear cholesteatoma
- VernacularTitle:IL-1?和MMP-9在中耳胆脂瘤上皮中的表达
- Author:
Junrong WEI
;
Xiaoyong REN
;
Guoxi ZHENG
- Publication Type:Journal Article
- Keywords:
interleukin-1?;
matrix metalloproteinase-9;
middle ear;
cholesteatoma
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of interleukin1?(IL-1?) and matrix metalloproteinase-9(MMP-9) in middle ear cholesteatoma and to explore the correlation between their expression and the ability of destruction of cholesteatoma.Methods IL-1? and MMP-9 were determined immunohistochemically in the specimens from 21 cases cholesteatomas and 10 external ear skin of patients with cholesteatoma.Results The positive expression of IL-1? and MMP-9 in cholesteatoma epithelialium were increased greatly than that in external epidermis(P
