The role of gap junction inhibitors in the epileptic animal model induced by injection of kainic acid
- VernacularTitle:缝隙连接抑制剂对海人藻酸致动物模型脑电活动的抑制作用
- Author:
Zhengxu CAI
;
Shuqin ZHANG
;
Qun LIU
;
Huishu GUO
- Publication Type:Journal Article
- Keywords:
Epilepsy;
Gap junctions;
Connexin 43;
Carbenoxolone;
Rats
- From:
Chinese Journal of Neurology
2005;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusions The gap junction formed by CX43 should be an important role in switching and developing the epilepsy. The synthetic polypeptide corresponding to amino acid sequence of CX43 would be a kind of new type antiepileptic drug, which might have less side effects and more potent pertinency.