Adjustment of immunosuppression and prevention of pulmonary infection in recipients of renal transplantation
- VernacularTitle:肾移植患者免疫抑制剂调整与预防呼吸道感染的关系
- Author:
Meisheng ZHOU
;
Youhua ZHU
;
Peifang ZHANG
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Lung;
Infection;
Therapeutics
- From:
Chinese Journal of Organ Transplantation
2005;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the adjustment of immunosuppression and prevention of infections in lung after renal transplantation.Methods 253 cases of pulmonary infections after renal transplantation between January 1999 to March 2004 were analyzed. After 2003, postinduction period, the blood concentrations of CsA and FK506 were maintained at 0.125~0.166 ?mol/L and 5 ?g/L respectively. The oral dose of MMF was 1 g every day. Results The creatinine levels were stable 253 patients after treatment. Among 253 cases, 229 cases were cured (90.51 %) and 24 died (9.49 %). After adjustment of immunosuppressants, common pulmonary infections and severe pulmonary infections were decreased.Conclusions Infection in lung was a severe complication after renal transplantation. Timely treatment, nursing care and adequate adjustment of immunosuppression may achieve satisfactory effects in preventing lung infection.
