An Experimental Study about Contrast Medium Injection Rate and Dose in Cerebral CT Perfusion Imaging
- VernacularTitle:脑CT灌注成像对比剂注射速率与剂量实验研究
- Author:
Libiao JI
;
Dehang WANG
;
Sheng LIU
;
Haibin SHI
- Publication Type:Journal Article
- Keywords:
injection rate;
injection dose;
perfusion imaging;
tomography,X-ray computed
- From:
Journal of Practical Radiology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the suitable injection rate and dose in multi-slice CT perfusion imaging.Methods Randomized block design was adopted in this study.The treatment factor-contrast medium injection rate was classified into 3,4,5,6 and 8 ml/s;thesubjects were divided into 5 blocks grouped by contrast medium injection dose: 0.5,0.75,1,1.25 and 1.5 ml/kg.25 Beagles wererandomly enrolled to undergo cerebral CT perfusion imaging.After post processing,time to peak(TTP) and rise value(RV) were measured in superior sagital venous.Results Injection rate had a significant effect on TTP of superior sagital venous.There was no significant difference among group 5,6 and 8 ml/s.Compared with 8 ml/s,TTP of superior sagital venous was prolonged when injection rate 3,4 ml/swere adopted.Injection dose had a significant effect on RV of superior sagital venous.There was no significant difference among group 1,1.25 and 1.5 ml/kg.In comparison with 1 ml/kg,RV of superior sagital venous was prolonged when injection dose 0.5 and 0.75 ml/kg were adopted.Conclusion The quality of cerebral CT perfusion imaging is well enough even injection rate as low as 5 ml/s or injection dose as few as 1 ml/kg.
