Valproate and topiramate induced weight and serum leptin change in epileptic patients
- VernacularTitle:丙戊酸钠、托吡酯诱导癫癎患者体重及血清瘦素水平的变化
- Author:
Xuhong YANG
;
Dong ZHOU
- Publication Type:Journal Article
- Keywords:
Anticonvulsants;
Body weight;
Leptin;
Valproic acid;
Fructose
- From:
Chinese Journal of Neurology
2005;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe weight and serum leptin changes in epileptic women who taking valproate or topiramate. Method All 40 epileptic women were treated with valproate or topiramate. Weight and body mass index and serum leptin were measured before and after three months treatment. Result Nine of 20 patients taking valproate gained weight (≥4 kg), and their serum leptin concentration was increased as well [(13.2?3.6) ng/ml vs (7.4?3.0)ng/ml, P
