The changes of D-D, t-PA and PAI in acute renal failure patients during blood purification and its clinical significance
- VernacularTitle:血液净化治疗急性肾衰时D-D、t-PA和PAI的改变及临床意义
- Author:
Yan TENG
;
Wujun XUE
;
Yazhuo JIANG
;
Heli XIANG
;
Hongli JIANG
- Publication Type:Journal Article
- Keywords:
acute renal failure(ARF);
blood purification;
D-dimer(D-D);
tissue-type plasminogen activator((t-PA));
plasminogen activator inhibitor(PAI)
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the dynamic changes and clinical significance of D-D, t-PA and PAI in patients with acute renal failure during the process of different methods of blood purification. Methods Thirty-seven ARF patients were divided into three groups: HD group, HDF group and HF group. Plasma D-D level, t-PA and PAI activity were determined 1 hour, 4 hours before and after treatment. Normal control group consisted of fourteen healthy people. Results ① Plasma D-D level and PAI activity in ARF patients were obviously higher than those in control group, while t-PA activity was lower(P0.05). ③ After 4 hours of the treatment, compared with HD group, HDF and HF groups had significant difference in plasma D-D level, t-PA and PAI activity(P
