Clinicopathological characritics and prognosis of large intestinal mucoid adenocarcinoma
- VernacularTitle:大肠粘液腺癌的临床病理特点及预后分析
- Author:
Miao ZHENG
;
Jikun LI
;
Lisheng ZHOU
- Publication Type:Journal Article
- Keywords:
large intestinal carcinoma;
largeintestinal muc oid adenocarcinoma;
clinical pathology
- From:China Oncology
1998;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the clinicopathological characristics of colorectal mucinous adenocarcinoma (MUC),which is generally bel ieved to have a poor prognosis,in an attempt to assess ways in which the surgica l outcome can be improved. Methods:From 1994 to 2003,1 715 large intestinal cancer patient s underwent operation, among them, 197 patients were with MUC. The clinicopathol ogical parameters and prognosis of MUC and non-MUC were analyzed retrospectivel y. Results:There were no significant differences in sex , tumor si te and size. Patients with MUC had higher rate of serosal invasion (MUC:59.9% vs non-MUC: 35.1%) , invasive type lymph-node involvement (MUC:41.6% vs non-MUC 21.6%). Patients with MUC were of more advanced stage(D stage:MUC :44.1% vs non-MUC: 22.1%). Conclusions:Based on these findings , a more aggressive attitud e toward surgical intervention is recommended , including extensive lymph node d issection and the resection of adjacent organs that seems to be affected microsc opically , to improve the surgical outcome of this clinical entity.
