Significance of plasma soluable thrombomodulin in type 2 diabetic patients
- VernacularTitle:2型糖尿病患者血浆中可溶性血栓调节蛋白的意义
- Author:
Xiaolong TANG
;
Shuyu CAI
;
Rongbo ZHANG
;
Xin ZHOU
- Publication Type:Journal Article
- Keywords:
Thrombomodulin;
Diabetes mellitus, type 2;
Protein C;
Antiplasmin
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Proteins in coagulative and fibrinolytic systems were measured in 50 type 2 diabetic patients and 50 normal controls. Proteins related with fibrinolytic system in the diabetic patients were significantly higher than those in normal controls. The concentration of soluble thrombomodulin (sTM) was negatively correlated with the activity of protein C and positively correlated with plasmin-? 2 -antiplasmin complex in type 2 diabetic patients, suggesting that the increase of sTM is associated with hypercoagulability and enhanced fibrinolysis.