Application of interventional ultrasound to prenatal diagnosis of fetal chromosomal abnormalities
- VernacularTitle:介入超声技术在产前诊断胎儿染色体异常中的应用研究
- Author:
Guowei TAO
;
Shaoping LIU
;
Qingzhao FU
;
Xinfeng ZHAN
- Publication Type:Journal Article
- Keywords:
Ultrasonography,interventional;
Fetus;
Chromosome abnormalities
- From:Chinese Journal of Ultrasonography
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of interventional ultrasound technique in prenatal diagnosis of fetal chromosomal abnormalities.Methods Percutaneous ultrasound-monitored amniocentesis and cordocentesis were performed on 186 pregnant women with indicantions for prenatal diagnosis to detect karyotype of the fetus.Results All the cases were punctured successfully.Percutaneous ultrasound-monitored amniocentesis was performed in 105 pregnant women.The archievement rate of the aminiotic fluid was 97.1%,and the detection rate of the chromosomal abnormality was 8.8%.Percutaneous ultrasound-monitored cordocentesis were performed in 81 pregnant women.The archievement rate of the cord blood was 98.8%,and the detection rate of the chromosomal abnormality was 5.0%.There was no significant deviation between them.The valid indications of the puncture included the abnormal serology screening results of pregnant women,the history of abnormal deliveries,the history of the trisomy 21,and the abnormal fetus detected by ultrasound,the last of which was higher than the other indications at the detection of the chromosomal abnormality.Conclusions Interventional ultrasound technique proves to be valid in the prenatal diagnosis,and ultrasound detection of abnormal fetus indicates the possibility of the fetal chromosomal abnormality.
