Techniques for improving the quality of the model of orthotopic liver transplantation in rats
- VernacularTitle:提高大鼠原位肝移植手术质量的技巧和注意事项
- Author:
Jinbiao LIU
;
Shuguo ZHENG
;
Yujun ZHANG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Microsurgery;
Rat
- From:
Chinese Journal of Organ Transplantation
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide a reliable model of orthotopic liver transplantation in rats and study surgical techniques for improving the quality of the operation. Methods The model was established by modified Kamada’s cuff technique. The time of cold preservation was 60 min. The successful rate of the method and one-week survival rate were observed. Results In 135 cases undergoing orthotopic liver transplantation, one-week survival rate was 89.2% . The successful rate of the model was 95.6% . Conclusions The key for success in rat liver transplantation is the shortened anhepatic period and delicate and skillful surgical manipulation. Also some detailed modified techniques should be used.